NRP369 is a conditionally
bioreversible derivative (CBD) of oxycodone, an opioid used
to treat chronic pain. Oxycodone is sold in an extended-release
form under the brand name OxyContin® and is used to treat
chronic pain. Oxycodone, either by itself or in combination
with non-opioid analgesics (e.g., Percodan® and Percocet®),
is a Schedule II drug with a very high propensity for abuse
and overdose.
NRP369 has been repositioned as a backup to NRP290, and the
company will not advance an IND on NRP369 until it reviews
sufficient clinical data on NRP290 to determine that NRP369
could enjoy a differentiated market position relative to NRP290.
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